FBCs to the rescue

Fat body cells are motile and actively migrate to wounds to drive repair and prevent infection.  Dev Cell, 44: 460–470.
Adipocytes have many functions in various tissues beyond energy storage, including regulating metabolism, growth, and immunity.  However, little is known about their role in wound healing.  Here we use live imaging of fat body cells, the equivalent of vertebrate adipocytes in Drosophila, to investigate their potential behaviors and functions following skin wounding.  We find that pupal fat body cells are not immotile, as previously presumed, but actively migrate to wounds using an unusual adhesion-independent, actomyosin-driven, peristaltic mode of motility.  Once at the wound, fat body cells collaborate with hemocytes, Drosophila macrophages, to clear the wound of cell debris; they also tightly seal the epithelial wound gap and locally release antimicrobial peptides to fight wound infection.  Thus, fat body cells are motile cells, enabling them to migrate to wounds to undertake several local functions needed to drive wound repair and prevent infections.

表皮の創傷治癒において、ショウジョウバエでは、損傷部位まで泳いで来た fat body cells（脂肪体の細胞：Drosophilaのadipocyte）が上皮の穴をふさぎ、マクロファージと協力しながら損傷細胞を除去し、そしてantimicrobial peptidesを分泌することにより細菌感染を防いでいる、という報告。スゴイなぁ、fat body cells、epithelial wound healingの中心的な役割を果たしていると言えそうなぐらい色々と重要なことやっとるやん。